NAD+
Physician-supervised compounded NAD+ for cellular-coenzyme support.
$179per 4 weeks
includes $30 clinician review
- Route
- Weekly IV/IM
- Frequency
- Once weekly
- Access
- Prescription only
What it is
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell, used in many metabolic reactions. The compounded injectable preparation is prescribed by a U.S.-licensed physician and prepared and dispensed by state-licensed pharmacies, including 503A compounding pharmacies.
The compounded preparation has not undergone finished-product efficacy testing for any specific indication and is not a treatment for any specific disease.
Details about NAD+
NAD+ acts as an electron carrier in mitochondrial reactions involved in energy metabolism, and serves as a substrate or cofactor for several other intracellular enzyme families. The body synthesizes NAD+ from dietary precursors and consumes it continually. Supplementation aims to support intracellular NAD+/NADH ratios under physician supervision; outcomes are individual and cannot be guaranteed.
Research on NAD+ and its precursors has been conducted in laboratory and clinical-research settings. The compounded preparation dispensed by the partner pharmacy is not the same as the NAD+ precursor products (NMN, NR) studied in those reports; the compounded preparation itself has not undergone equivalent finished-product efficacy testing. Your physician will discuss realistic expectations at consultation.
- Cellular-coenzyme support under physician supervision
- Subcutaneous administration with a schedule determined by your physician
- Patient-reported outcomes often described include changes in subjective energy or mental clarity (individual; outcomes not guaranteed)
- Report a side effect from your portal at any time
- Chest tightness or pressure during IV infusion (dose-rate dependent)
- Nausea, particularly with higher doses
- Flushing and warmth at injection site
- Headache
- Mild cramping
- Fatigue during initial treatment (temporary as cells adapt)
- Active cancer (NAD+ may support rapidly dividing cells)
- Pregnancy or breastfeeding
- Known hypersensitivity to NAD+ or any formulation components
- Severe liver disease
- Chemotherapy agents - NAD+ may affect drug metabolism; consult oncologist
- Blood pressure medications - NAD+ may have mild vasodilatory effects
- Diabetes medications - monitor blood glucose as NAD+ may improve insulin sensitivity
Follow the storage instructions provided by our pharmacy and on the medication label.
Questions about NAD+
Patient experience varies. Some patients describe a subjective change in energy or mental clarity in the first few weeks; others report no change. NAD+ is not a treatment for any specific disease and outcomes cannot be guaranteed. Your Pep Club physician will discuss realistic expectations at consultation.
Yes. The compounded NAD+ preparation dispensed by the partner pharmacy is administered as a subcutaneous injection. Oral NAD+ precursors (NMN, NR) are different products with different routes and different absorption profiles. Your physician will discuss which approach fits your situation.
Where it is available
Available where The Pep Club has a licensed physician and a licensed pharmacy partner. See the state availability page for the current list.
Ready when you are.
Get started in two minutes and we confirm we ship to your state. A licensed physician takes it from there.
Compounded preparation
This is a compounded preparation, prepared by state-licensed pharmacies, including 503A compounding pharmacies, under U.S.-licensed physician supervision. Compounded medications are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before they reach patients. A compounded preparation is not a generic version of, and is not the same as, any FDA-approved medication. It is prescribed only when a licensed provider decides it is appropriate for you. Patients are screened and supervised by U.S.-licensed physicians throughout treatment.