Anti-Aging
NAD+
Starting at
$149/mo
Physician-supervised compounded NAD+ for cellular-coenzyme support.
- Route
- Weekly IV/IM
- Frequency
- Once weekly
- Access
- Prescription only
- Billing
- Monthly, cancel anytime
What it is
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell, used in many metabolic reactions. The compounded injectable preparation is prescribed by a U.S.-licensed physician and prepared and dispensed by a licensed compounding pharmacy.
The compounded preparation has not undergone finished-product efficacy testing for any specific indication and is not a treatment for any specific disease.
NAD+ clinical details
NAD+ acts as an electron carrier in mitochondrial reactions involved in energy metabolism, and serves as a substrate or cofactor for several other intracellular enzyme families. The body synthesizes NAD+ from dietary precursors and consumes it continually. Supplementation aims to support intracellular NAD+/NADH ratios under physician supervision; outcomes are individual and cannot be guaranteed.
Research on NAD+ and its precursors has been conducted in laboratory and clinical-research settings. The compounded preparation dispensed by the partner pharmacy is not the same as the NAD+ precursor products (NMN, NR) studied in those reports; the compounded preparation itself has not undergone equivalent finished-product efficacy testing. Your physician will discuss realistic expectations at consultation.
- Cellular-coenzyme support under physician supervision
- Subcutaneous administration with a schedule determined by your physician
- Patient-reported outcomes often described include changes in subjective energy or mental clarity (individual; outcomes not guaranteed)
- Physician follow-up consultations review tolerability and adjust the protocol
- Chest tightness or pressure during IV infusion (dose-rate dependent)
- Nausea, particularly with higher doses
- Flushing and warmth at injection site
- Headache
- Mild cramping
- Fatigue during initial treatment (temporary as cells adapt)
- Active cancer (NAD+ may support rapidly dividing cells)
- Pregnancy or breastfeeding
- Known hypersensitivity to NAD+ or any formulation components
- Severe liver disease
- Chemotherapy agents - NAD+ may affect drug metabolism; consult oncologist
- Blood pressure medications - NAD+ may have mild vasodilatory effects
- Diabetes medications - monitor blood glucose as NAD+ may improve insulin sensitivity
Follow the storage instructions provided by your pharmacy and on the medication label.
NAD+ frequently asked questions
Patient experience varies. Some patients describe a subjective change in energy or mental clarity in the first few weeks; others report no change. NAD+ is not a treatment for any specific disease and outcomes cannot be guaranteed. Your Pep Club physician will discuss realistic expectations at consultation and monitor progress.
Yes. The compounded NAD+ preparation dispensed by the partner pharmacy is administered as a subcutaneous injection. Oral NAD+ precursors (NMN, NR) are different products with different routes and different absorption profiles. Your physician will discuss which approach fits your situation.
Availability
Available where The Pep Club has a licensed physician and a licensed pharmacy partner. See the state availability page for the current list.
Also in the formulary
Ready when you are.
A two-minute eligibility check tells you if we ship to your state. A licensed physician takes it from there.
Compounded preparation
This is a compounded preparation prepared by a licensed compounding pharmacy under U.S.-licensed physician supervision. Patients are screened and supervised by U.S.-licensed physicians throughout treatment.